Windows system allows to install more than one MCI compatible MIDI devices (sound card, software synthesizer, external MIDI device connection, ...).
GNMIDI internal player plays MIDI files through the device selected from this list of output devices.
This setting does not affect external MIDI players, they should have their own settings.
MidiMapper
Choose MidiMapper if you want to use the device that is used by Mediaplayer as standard output device.